FMoc-2,4-DiaMinobutyric acid dihydrochloride

FMoc-2,4-DiaMinobutyric acid dihydrochloride - Names and Identifiers

Name	(2S)-4-Amino-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid hydrochloride
Synonyms	FMoc-2,4-DiaMinobutyric acid dihydrochloride (2S)-4-Amino-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]buta... (2S)-4-amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid N-α-(9-Fluorenylmethoxycarbonyl)-L-α,γ-diaminobutyric acid hydrochloride [(3S)-3-carboxy-3-(9H-fluoren-9-ylMethoxycarbonylaMino)propyl]aMMoniuM chloride (2S)-4-Amino-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid hydrochloride (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-aminobutanoic acid hydrochloride
CAS	366491-49-8

FMoc-2,4-DiaMinobutyric acid dihydrochloride - Physico-chemical Properties

Molecular Formula	C19H20N2O4.HCl
Molar Mass	377
Storage Condition	Sealed in dry,Room Temperature

FMoc-2,4-DiaMinobutyric acid dihydrochloride - Introduction

(2S)-4-Amino -2-[[(9H-Fluoren-9-ylmethoxy) carbonyl] amino] butanoic acid hydrochloride is a chemical substance with the following properties:

Physical and chemical properties:
-Appearance: White crystal or crystalline powder
-Molecular formula: C25H25N2O4 · HCl
-Molecular weight: 480.93g/mol
-melting point: about 160-165 ℃
-Solubility: Soluble in water and some organic solvents

Use:
-Biomedical Research: As an important amine protecting group, it is often used to change chemical properties, increase anti-metabolic ability and increase solubility in peptide synthesis and drug development.
-Pharmaceutical preparations: for the preparation of peptide drugs, peptide antibiotics and biologically active small molecules.
-Drug Guide: In drug delivery, it can improve drug selectivity and reduce toxicity.

Preparation Method:
The preparation method of (2S)-4-amino -2-[[(9H-fluoren-9-ylmethoxy) carbonyl] amino] butyric acid hydrochloride can be achieved by the following steps:
1. firstly, (9H-fluorene -9-yl formaldehyde) is added to dimethylformamide to obtain (9H-fluorene -9-yl methoxy) aldehyde.
2. condensation reaction of (9H-fluorene -9-ylmethoxy) aldehyde with formyl propyl amino acid to generate (2S)-4-amino -2-[[(9H-fluorene -9-ylmethoxy) carbonyl] amino] butyric acid.
3. finally, the obtained product is reacted with hydrochloric acid to prepare (2S)-4-amino -2-[[(9H-fluoren-9-ylmethoxy) carbonyl] amino] butyric acid hydrochloride.

Safety Information:
-Take appropriate safety precautions during operation and use, including wearing chemical protective gloves and glasses.
-Avoid inhalation of powder or contact with skin, avoid ingestion.
-In case of contact, rinse immediately with plenty of water and seek medical help.
-should be stored in a dry, well-ventilated place, away from fire and combustible materials.
-Detailed safety information can be found in the safety data sheet of the chemical.

Last Update：2024-04-09 15:17:58